Preparation and Anti-Tumor Activity of mesoporous silica nanoparticles (MSN) containing both free an

来源 :中国微米纳米技术学会纳米科学技术分会第三届年会暨2014全国纳米生物与医学学术会议 | 被引量 : 0次 | 上传用户：fang82888

【摘要】

：

【作者】

：

Ting Chi Liping Xiang Xiang Yang Qiao Tang Xiaobo Yu Jian Liu Yajun Liu Jingjing Xie Jingwei Shao Lee Jia

【机构】

：

Cancer Metastasis Alert and Prevention Center,College of Chemistry,Biopharmaceutical Photocatalysis,

【出处】

：

中国微米纳米技术学会纳米科学技术分会第三届年会暨2014全国纳米生物与医学学术会议

【发表日期】

：

2014年6期

【关键词】

：

Ursolic acid mesoporous silica nanoparticle anti-tumor activity

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　Mesoporous silica nanoparticles(MSNs)are a promising material for drug delivery.We delicately prepared a mesoporous silica nanoparticle(MSN)for the delivery of low water solubility drug to tumor cells.In this study,mesoporous silica MCM-41 nanoparticles were used as the core for loading antineoplastic compound ursolic acid(UA).Meanwhile,the ursolic acid(UA)was covalently conjugated to the surface of nanoparticles.

其他文献

Overcoming drug-resistant lung cancer by paclitaxel loaded dual-functional liposomes with mitochondr

Mitochondrion-orientated transportation of smart liposomes has been developed as a promising strategy to deliver anticancer drugs directly to tumor sites,and these have a tremendous potential for kill

会议

A Novel Technique for Detection and Isolation of Nanometer Circulating Tumor cells for Predicting Tu

Rare circulating tumor cells (CTCs) are present in the bloodstream of millions of patients and increasing asymptomatic cancer survivors and are the root cause of cancer metastases and deaths.Current s

会议

Enhanced Restraining Circulating Colorectal Cancer Cells in Blood and Their Hetero-Adhesion to Endot

Dissemination of circulating tumour cells (CTCs) to potential metastatic sites mostly occurs in the circulation system.CTCs in blood and their hetero-adhesion to vascular endothelial bed of distant me

会议

Recognition and Down-Regulation of Circulating Tumor Cells by Dual-Aptamer-Coated Mesoporous Silica

The main reason for most cancer deaths is tumor metastasis.Circulating tumor cells (CTCs) are thought to be responsible for metastasis,so the capturing and restraining of CTCs may serve as an efficien

会议

New molecular beacon for detection of p53 gene point mutation and its potential as a primer for poly

Due to the relatively mature technologies to manipulate nucleic acids at will and the intrinsic properties of these biomacromolecules,oligonucleotides are widely explored as detection probes to develo

会议

Nanoparticle-assisted combination therapy against triple negative breast cancer by using miR-34a and

Metastatic relapse,development of drug resistance in cancer cells and adverse side effects of chemotherapeutic agents are the major obstacles for effective chemotherapy against triple-negative breast

会议

NanoparticlesCo-deliveryMicroRNA-34aDoxorubicinCombined therapy

Natural polymer-protein conjugates in oral vaccine formulations

Oral vaccines have potential advantages over injected ones to provide effective mucosal and systemic immunity due to their non-invasive nature,lower production costs,as well as higher practicality and

会议

模拟微重力体外构建组织工程神经的研究

应用含支持细胞的组织工程化神经修复长距离周围神经缺损己经成为一个研究热点。然而，在以往的研究中采用直接注射法存在支持细胞流失、细胞状态未知、归属难于把握等诸多不可控因素。

会议

周围神经组织工程体外构建生物反应器皮肤源性前体细胞

The Differential Cytotoxicity of Water-soluble Fullerene Derivatives by Improved Nitrene Chemistry

Water-solublefullerenes,C60[N(CH2)2OH]12,C60[N(CH2)2NH2]10,and C60[N(CH2)2COOH]10,were synthesized by improved nitrene chemistry[1],which C60 was reacted with azide small molecules(N3(CH2)2OH,N3(CH2)2

会议

Water-soluble Fullerene DerivativesNitrene ChemistryCytotoxicity

Nanopore-based tetracycline detection

rtTA(reverse tetracycline-controlled transactivator) and TRE(Tetracycline Responsive Element) will bind to each other under the action of tetracycline and form one complex.When this complex passes thr

会议

Preparation and Anti-Tumor Activity of mesoporous silica nanoparticles (MSN) containing both free an

与本文相关的学术论文