Objective: A retrospective study had been conducted to compare the existing preoperative scoring systems and to find useful prognostic factors for patients with spinal metastases from hepatocellular carcinoma (HCC).Objective.To evaluate different preoperative scoring systems and prognostic factors for patients with spinal metastases from HCC.Methods: We conducted a retrospective study to evaluate four prognostic scoring systems and factors in a series of 41 cases with spinal metastases from HCC in a single center.These scoring systems include Tokuhashi revised score, Tomitas score, Bauers score and a revised van der Lindens score by the authors.Serologic test items including serum albumin, aspartate arminotransferase, alanine transarninase and lactate dehydrogenase also were evaluated.Results.The revised Tokuhashi scoring system provided statistically significant differences in survival time between different groups (p=0.012), while the Tomita and Bauer systems did not show statistically significant differences (p=0.918 and p=0.754, respectively).Significantly improved survival was found in patients with goodperformance status and no visceral metastases (Group C, P=0.008) in revised van der Linden scores.Univariate and multivariate analysis showed serum albumin and lactate dehydrogenase (LDH) were independent prognostic factors for survival time.Coneulsion: Revised Tokuhashi scoring system is practicable and highly predictive, while serum albumin and LDH also have prognostic value in patients with spinal metastases from HCC, especially those without visceral metastases.More accurate prognosis may be obtained if the scoring systems include clinical and laboratory data in future.