Variable Roles of the Spiroindolenines in Pictet-Spengler Reactions:Insights from DFT Calculations a

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【摘要】

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【作者】

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Chao Zheng Shu-Li You

【机构】

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Key Laboratory of Organometallic Chemistry,Shanghai Institute of Organic Chemistry,Chinese Academy o

【出处】

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第十二届全国物理有机化学学术会议

【发表日期】

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2017年10期

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Pictet–Spengler reactions have been extensively utilized in the synthesis of various indole alkaloids.Meanwhile,their mechanistic aspect is really intriguing and has been a controversial research topic for quite a long time.1 Spiroindolenines has long been proposed as a key intermediate in Pictet–Spengler reactions.

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Variable Roles of the Spiroindolenines in Pictet-Spengler Reactions:Insights from DFT Calculations a

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