【摘 要】
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AIM: To investigate the effect of metformin on cardiac fibrosis and the underlying mechanisms.METHODS:Ten-week-old male mice (C57BL/6) were subjected to left ventricular pressure overload by transvers
【机 构】
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Institute of Vascular Medicine of Peking University Third Hospital,Ministry of Health Key Laboratory
【出 处】
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中国病理生理学会心血管专业委员会第十五届学术大会暨国际心脏研究会中国分会第十二届学术大会
论文部分内容阅读
AIM: To investigate the effect of metformin on cardiac fibrosis and the underlying mechanisms.METHODS:Ten-week-old male mice (C57BL/6) were subjected to left ventricular pressure overload by transverse aortic constriction.The mice received metformin (200 mg· kg-1 · d-1) or normal saline for 6 weeks.
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