PDZK1 Controls Proliferation in Renal Tumor Cells by Regulating SHP-1 Phosphorylation

来源 :首都医科大学第三届研究生学术论坛 | 被引量 : 0次 | 上传用户:jiajiayou123123
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  Renal cell carcinoma (RCC) is the most lethal of the common urologic cancer and associated with a poor prognosis.Although many reports have investigated the tumor suppressor protein tyrosine phosphatase non-receptor type 6 (PTPN6 or SHP-1) in hematopoietic cells, comparatively few reports have looked at the biological importance of SHP-1 in solid tumors.
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