For establishment of cancer immunotherapy,efficient antigen carriers are needed to deliver antigen into the cytosol of dendritic cells (DCs) and induce antigen-specific cellular immune responses.pH-Sensitive liposomes are useful as an intracellular delivery system for their ability to transfer their contents into the cytosol by iH-resionsive fusion with endosomal membrane.We previously reported cytoplasmic delivery using liposomes modified with carboxylated poly(glycidol)s [1].