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  5. Effect of CYP2C192 and *3 alleles on platelet reactivity and adverse clinical events in Chinese clop

Effect of CYP2C192 and *3 alleles on platelet reactivity and adverse clinical events in Chinese clop

来源 :第11届中国介入心脏病学大会 | 被引量 : 0次 | 上传用户：lqym2929
【摘 要】
：
Background As compared with whites, Chinese people more often carry the cytochrome P450 (CYP) 2C19loss-of-function (LOF) allele with the CYP2C193 variant and less carry the cytochrome P450 (CYP) 2C19g
【作 者】
：
TANG Xiao-fang YUAN Jin-qing YANG Yue-jin 
【机 构】
：
Fuwai Hospital,Beijing,China
【出 处】
：
第11届中国介入心脏病学大会
【发表日期】
：
2013年7期
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Background As compared with whites, Chinese people more often carry the cytochrome P450 (CYP) 2C19loss-of-function (LOF) allele with the CYP2C193 variant and less carry the cytochrome P450 (CYP) 2C19gain-of-function (GOF) allele with the CYP2C 19* 17.This study aimed to investigate the effect of the CYP2C 19 variants on clopidogrel pharmacodynamics and long-term prognosis in these patients.
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