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Background As compared with whites, Chinese people more often carry the cytochrome P450 (CYP) 2C19loss-of-function (LOF) allele with the CYP2C193 variant and less carry the cytochrome P450 (CYP) 2C19gain-of-function (GOF) allele with the CYP2C 19* 17.This study aimed to investigate the effect of the CYP2C 19 variants on clopidogrel pharmacodynamics and long-term prognosis in these patients.