Bidirectional regulation of the skin permeability of indapamide and bisoprolol in their compound tra

来源 :2014年中国药物制剂大会——中国药学会药剂专业委员会年会、第六届亚洲阿登制药技术研讨会暨国际控释协会中国分会年会 | 被引量 : 0次 | 上传用户:chenman1982
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Objective: To achieve the synchronous skin permeation of indapamide (IND) and bisoprolol (BSP), two drugs with totally different skin permeability, the technique of ion-pair complexation and chemical enhancers were combined to bi-directionally regulate the skin permeability of IND and BSP in their compound transdermal patct.
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