Quantifying the Genetic Control of Disease Proteotypes by DataIndependent Acquisition

来源 :第五届中国计算蛋白质组学研讨会 | 被引量 : 0次 | 上传用户:lulufii
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  variability,the rapid evolution of genomic variability in culture and a complex translation of genomic variability into expressed molecular and phenotypic variability.By associating quantitative proteotype and phenotype measurements we identified protein patterns that explained the varying response of the different cell lines studied to bacterial infection.Our data further highlights a proteomic understanding of "gene dosage imbalance" in genetic disorders and cancer cells.
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