【摘 要】
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The big bang of the data produced by next-generation proteomics requires a powerful,integrated,online data processing and analyzing platform able to host millions of datasets and analyze hundreds and
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The big bang of the data produced by next-generation proteomics requires a powerful,integrated,online data processing and analyzing platform able to host millions of datasets and analyze hundreds and thousands of experiments simultaneously.However,such a platform has not yet been developed.In this correspondence,we report Firmiana(V1.0)(www.firmiana.org),a one-stop proteomic data processing and integrated omics analysis cloud platform that allows scientists to deposit MS raw files,perform proteome identification/quantification online,carry out bioinformatics analyses,extract knowledge,and visualize results using a biologist-friendly web interface in an automated,high-throughput fashion and without the need for programming expertise.As a big data platform,Firmiana 1.0 can connect to other repositories for data migration and to achieve the multi-omics integration of life sciences.The high-Firmiana transferring,and the finished modules have exhibited significant increase in speed and capability in the HPC environment.To date,Firmiana 1.0 has hosted,processed,and presented over 794M spectra from 18,337 experimental datasets(approximately 31,223 MS files),covering 39,795 gene products from 10 species.We envision that Firmiana 1.0 and its subsequent Firmiana 2.0 be released based on the HPC will provide an online resource for the proteomics and biology community to take advantage of proteomics in the big data era,bridging proteomics to biol.
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