Neuronal Model Reduction: Cells, Junctions and Circuits

来源 :2014第五届国际神经科技大会暨2014首届国际高科技针灸和中西医结合大会 | 被引量 : 0次 | 上传用户:awubang
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  The spatial component of input signals often carries information crucial to a neurons function, but models which map synaptie inputs to transmembrane potential can be eomputationally expensive.Existing reduced models of the neuron either merge compartments, thereby sacrificing the spatial specificity of inputs, or apply model reduction techniques which sacrifice the biological interpretation of the model.
其他文献
Recent research in various regions of the brain has unveiled ubiquitous functions of adult neurogenesis.Converging results from studies of the hippocampus to the hypothalamus across multiple species p
会议
Faults in a batch process model of the small intestine create the symptoms of all types of irritable bowel syndrome.The model has three sequential processing sections corresponding to the natural divi
会议
Early life stress has been related to emotional and behavioral disorders later in life.Children exposed to aversive environments are at risk to develop psychopathologics.The understanding of the mecha
会议
Through their capacity to secrete, upon activation, a variety of bioactive molecules mononuclear phagocytes (brain macrophagesand resident microglia) play an important role in brain immune and inflamm
会议
Microglia plays a crucial role in the pathogenesis of HIV-l-associated neurocognitive disorders.Increasing evidence indicates the voltage-gated potassium (KV) channels are involved in the regulation o
会议
Inflammation in the central nervous system (CNS) is a complex process with a high social and economic impact worldwide.Currently there is no effective therapy for prevention and treatment of CNS infla
会议
Glial cell line-derived neurotrophic factor (GDNF), either secreted from neural stem cells that were grafted into the injured rat brains in vivo or given directly to injured neurons in vitro, effectiv
会议
Emerging evidence increasingly suggests that neural stem cells (NSCs) may repair the central nervous system (CNS) through innate multimechanistic strategies that are often concurrent (i.e.,functional
会议
Genetic reprogramming of patient-derived fibroblasts to motor neurons via induced pluripotent stem cells (iPSc) offers fascinating perspectives for modeling, drug testing and cell replacement in degen
会议
Human Mesenchymal Stem Cells (hMSC) have become one of the most promising candidates for tissue engineering and regenerative medicine applications.However our knowledge about general nature and biolog
会议