Expression, purification and characterization of the two-state behavior of Mad2

来源 :2013年第四届全国“跨学科蛋白质研究”学术讨论会 | 被引量 : 0次 | 上传用户：cxwycn

【摘要】

：

　　A given protein generally has only one native tertiary fold, which is the conformation with the lowest Gibbs free energy.Mad2, a protein involved in the spi

【作者】

：

赵园园黄方

【机构】

：

中国石油大学(华东)-生物工程与技术中心,蛋白质分子工程实验室,青岛266555

【出处】

：

2013年第四届全国“跨学科蛋白质研究”学术讨论会

【发表日期】

：

2013年10期

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　　A given protein generally has only one native tertiary fold, which is the conformation with the lowest Gibbs free energy.Mad2, a protein involved in the spindle checkpoint, however, has two natively folded states with similar Gibbs free energies.

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Expression, purification and characterization of the two-state behavior of Mad2

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