Epigenetic regulation of microRNA expression by EZH2 in cancer and its therapeutic implication

来源 :第五届中国小核酸技术与应用学术会议 | 被引量 : 0次 | 上传用户：freedomo

【摘要】

：

The dysregulation of microRNA expression in pancreatic ductal adenocarcinoma (PDAC) has been well documented.However,the underlying mechanism is not fully explo

【作者】

：

Yangchao Chen

【机构】

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SchoolofBiomedicalSciences,FacultyofMedicine,TheChineseUniversityofHongKong,Shatin,HongKongSAR

【出处】

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第五届中国小核酸技术与应用学术会议

【发表日期】

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2015年9期

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The dysregulation of microRNA expression in pancreatic ductal adenocarcinoma (PDAC) has been well documented.However,the underlying mechanism is not fully explored.Enhancer of zeste homolog 2 (EZH2) is a histone methyltransferase and is overexpressed in PDAC.

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Epigenetic regulation of microRNA expression by EZH2 in cancer and its therapeutic implication

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