【摘 要】
：
Objectives Apelin is a recently-discovered cardiovascular bioactive polypeptide with multiple biological effects, which is the endogenous ligand of the orphan G protein-coupled receptor-APJ receptor a
【机 构】
：
State Key Laboratory of Medical Genomics,Ruijin Hospital Affiliated to Shanghai Jiao Tong University
【出 处】
：
第二十四届长城国际心脏病学会议、亚太心脏大会暨国际心血管病预防与康复会议(The 24th Great Wall Int
论文部分内容阅读
Objectives Apelin is a recently-discovered cardiovascular bioactive polypeptide with multiple biological effects, which is the endogenous ligand of the orphan G protein-coupled receptor-APJ receptor and may cause vasodilation and lower blood pressure levels.
其他文献
Objectives To investigate the correlation between C171T mutation of the potassium inwardly-rectifying channel, subfamily J,member 5 (KCNJ5) gene, and the hypokalemic primary aldosteronism (PA).Methods
Objectives To investigate the effects of activation of Autophagy on cerebral injury after cardiopulmonary resuscitation (CPR) in Wistar rat.Methods First 36 healthy adult male Wistar rats were induced
Objectives This study aimed to test the protection of puerarin in oxidative stress-induced mitochondrial injury in rat cardiac H9c2 cells.Methods Rat heart tissue-derived H9c2 cells were used.First, w
Objectives To investigate the myocardial proliferation/regeneration and myocardial cell apoptosis during different time points and in different parts of the heart in acute myocardial infarction (AMI)
Objectives CD36, a class B scavenger receptor expressed on macrophages mediates uptake of oxLDL and contributes to foam cell formation, a hallmark of early atherosclerosis.Tobacco smoking is a major r
Objectives To investigate the effects of advanced glycation endproducts (AGEs) on apoptosis and telomere length of human adiposetissue-derived stem cells (ADSCs) and the related molecular mechanism.Me
Objectives In ventricular fibrillation, the uncoupling of gap junctions slows conduction velocity and increases action-potential dispersion, which slows and diminishes defibrillation.We studied how th
Objectives To study the effect of activated β3-AR on reverse cholesterol transport and arterial atherosclerotic plaques in apolipoprotein E knockout (ApoE-/-) mice.Methods Ten wide type C57BL/6J mice,
Objectives Cellular repressor of E1A-stimulated genes (CREG) plays an important role in phenotypic modulation of VSMCs,but the mechanism of its upstream signalling regulation is not clear.Recently, mi
Objectives Cellular repressor of E1A-stimulated genes (CREG) is a mannose-6-phosphate-containing secreted glycoprotein of 220 amino acids.It has been proposed that CREG acts as a ligand that enhances