THE MECHANISM OF PUERARIN-INDUCED MITOCHONDRIAL PROTECTION

来源 :第二十四届长城国际心脏病学会议、亚太心脏大会暨国际心血管病预防与康复会议(The 24th Great Wall Int | 被引量 : 0次 | 上传用户:lwzeta
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Objectives This study aimed to test the protection of puerarin in oxidative stress-induced mitochondrial injury in rat cardiac H9c2 cells.Methods Rat heart tissue-derived H9c2 cells were used.First, we test if puerarin could modulate the mPTP opening.To detect the mPTP opening, cells were loaded with TMRE and imaged with confocal microscopy.
其他文献
Objectives To investigate the relationship and molecular mechanism of lincRNA-p21 in the development of atherosclerosis (AS).Methods Firstly, we detected the expression of lincRNA-p21 expression in th
会议
Objectives We studied if and how PHD2 silencing in human adipose-derived stem cells (ADSCs) enhances their cardioprotective effects after transplantation into infarcted hearts.Methods ADSCs were trans
会议
Objectives Hypertension is a very important risk factor for cardiac vascular disease.Our previous study showed that mitochondrial DNA mutations are associated with cardiovascular disease,including hyp
会议
Objectives To determine whether or not exogenous Cyclin-A2 promotes cardiac self-repair and restart cardiomyocytes cycle in vivo after MI.Methods Sixty mice were randomly divided into two groups;MI +
会议
Objectives Atrial fibrillation (AF) is associated with significant morbidity and mortality.Substantial evidence suggests that the renin angiotensin system (RAS) has a role in the pathogenesis of AF.An
会议
Objectives Diabetic patients continued to develop vascular complications despite achieving normal glucose level, suggesting metabolic memory which was associated with histone H3 lysine (H3K9) methylat
会议
Objectives Small interfering RNA (siRNA) methodology suppresses specific gene expression, thus mimicking loss-of-function mutation and enabling in vitro and in vivo gene function analysis.siRNA techno
会议
Objectives To study the expression Prohibitin in proliferation vascular smooth muscle cells (VSMCs) after balloon injure in rat carotid artery.Methods Twenty-four male SD rats of SPF grade were random
会议
Objectives To investigate the correlation between C171T mutation of the potassium inwardly-rectifying channel, subfamily J,member 5 (KCNJ5) gene, and the hypokalemic primary aldosteronism (PA).Methods
会议
Objectives To investigate the effects of activation of Autophagy on cerebral injury after cardiopulmonary resuscitation (CPR) in Wistar rat.Methods First 36 healthy adult male Wistar rats were induced
会议