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  5. Deletion of Angiotensin-Converting Enzyme 2 exacerbates kidney inflammation and injury in the apolip

Deletion of Angiotensin-Converting Enzyme 2 exacerbates kidney inflammation and injury in the apolip

来源 :Ready for 2018- the 4th China International Forum on Hyperte | 被引量 : 0次 | 上传用户：beret85
【摘 要】
：
Background:Angiotensin-converting enzyme 2 (ACE2) is known as a negative regulator of the RAS, but its role in atheroscierotic renal injury are poorly understood.We hypothesized that ACE2 would exert
【作 者】
：
Zhenzhou Zhang Laijiang Chen Yingle Xu Ran Xu Qing Chang Pingjin Gao Dingliang Zhu Jiguang Wang Jiuchang Zhong 
【机 构】
：
Shanghai Institute of Hypertension & State Key Laboratory of Medical Genomics,Ruijin Hospital Affili
【出 处】
：
Ready for 2018- the 4th China International Forum on Hyperte
【发表日期】
：
2015年3期
【关键词】
：
angiotensin-converting enzyme 2 inflammation atherosclerosis renal injury apolip 
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　　Background:Angiotensin-converting enzyme 2 (ACE2) is known as a negative regulator of the RAS, but its role in atheroscierotic renal injury are poorly understood.We hypothesized that ACE2 would exert beneficial effects on renal injury in apolipoprotein E (ApoE)-knockout (KO) mice.
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