Correlation between LRRK2 Gene G2019S, R1441C Mutation and Parkinson's disease

来源 :2015中国老年医学和老年健康产业大会 | 被引量 : 0次 | 上传用户：cxycsnf

【摘要】

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OBJECTIVE: The aim of this study was to discuss the correlation between LRRK2 gene G2019S mutation, R1441C mutation and Parkinsons disease in Uygur.METHODS: One-hundred and Thirty cases were selected

【作者】

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X.X.Li Q.Luo X.L.Yang

【机构】

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Neurological Center, the First Affiliated Hospital of Xinjiang Medical University, Urumqi, China

【出处】

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2015中国老年医学和老年健康产业大会

【发表日期】

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2015年7期

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OBJECTIVE: The aim of this study was to discuss the correlation between LRRK2 gene G2019S mutation, R1441C mutation and Parkinsons disease in Uygur.METHODS: One-hundred and Thirty cases were selected and were divided into two groups: the case group (130 cases), control group (179 cases).Then, their LRRK2 geneG2019S and R1441C mutation were analyzed by the polymerase chain reaction (restriction fragment length polymorphism (PCR-RFLP)) and DNA sequencing method.

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Correlation between LRRK2 Gene G2019S, R1441C Mutation and Parkinson's disease

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