【摘 要】
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Porcine circovirus associated disease (PCVAD) describes a group of complex syndromes such as porcine multi-systemic wasting syndrome (PMWS) and porcine dermatitis and nephropathy syndrome (PDNS).The c
【机 构】
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Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State Uni
【出 处】
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2013国际猪繁殖与呼吸综合征学术研讨会
论文部分内容阅读
Porcine circovirus associated disease (PCVAD) describes a group of complex syndromes such as porcine multi-systemic wasting syndrome (PMWS) and porcine dermatitis and nephropathy syndrome (PDNS).The central feature of PCVAD involves infection with porcine circovirus type 2 (PCV2).The capsid protein (CP) of PCV2 possesses an immunodominant epitope,CP(169-180),which is linked to infection with PCV2 and pathogenesis of porcine circovirus associated disease (PCVAD).For example,sera from pigs diagnosed with PCVAD,experimentally infected with PCV2,or vaccinated with baculovirus expressed CP recognize a polypeptide comprised of the entire CP minus the nuclear localization signal,CP(43-233) in an ELISA.
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