【摘 要】
：
Background B-lineage acute lymphoblastic leukemia (B-ALL) represents the most common subtype in ALL.Genomic sequence information has been lacking in adult B-ALL,whose outcome remains dismal,while a co
【机 构】
：
Rui Jin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
【出 处】
：
The 35th World Congress of the International Society of Hema
论文部分内容阅读
Background B-lineage acute lymphoblastic leukemia (B-ALL) represents the most common subtype in ALL.Genomic sequence information has been lacking in adult B-ALL,whose outcome remains dismal,while a comparison between genomic abnormalities in adult and pediatric groups is useful to further decipher disease mechanisms.
其他文献
基于150t顶底复吹转炉,采用单渣法工艺进行脱磷,分析研究了炉料结构和终点条件对脱磷的影响.结果表明,最佳的炉料结构为:一次吨钢辅料、一次辅料加入比例、总辅料吨钢量以及(石灰和石灰石)吨钢加入量分别控制在70kg/t～80kg/t、65％～75％、≥100kg/t和51kg/t～62kg/t之间;最佳的终渣条件为:终点温度、终渣FeO、碱度、MgO、MnO含量分别控制在1620℃～1640℃、22
目的：总结中医综合新疗法治疗跟骨骨刺症的临床疗效和护理.方法：采用针刺、中药湿敷、电磁波治疗仪温烤综合治疗法,治疗跟骨骨刺症患者50例.结果：显效39例,有效7例,好转4例.结论：针刺加TDP 治疗，综合了针灸、中药及理疗的作用，体现了中医多种治疗手段综合利用的特点，有利于提高临床疗效。针刺绝骨穴，既可补髓壮骨又能通经活络；川芎为血中之气药，有活血行气、消散瘀血的双重功效；TDP 照射的热作用，可
Although patients with acute myeloid leukemia (AML) and the t(8;21) translocation generally have a favorable prognosis,relapse occurs in about 40 ％of cases and long-term (＞5years) survival less than 5
After 2009,novel gene mutations were found in acute myeloid leukemia (AML) by using next-generation sequencing (NGS) methods.They are found in the epigenome-associated enzymes (TET2,IDH1/2,DNMT3A,ASXL
In addition to hematopoietic stem cells,the bone marrow also contains mesenchymal stromal cells (MSCs).These cells were first recognized more than 40 years ago by Friedenstein et al.who described a po
Acute myeloid leukemia (AML) is a heterogeneous group of hematologic malignancies with various clinical features and treatment outcomes.Risk-adapted treatment may not only improve the prognosis,but al
Background and Aim Mutations in the calreticulin (CALR) gene were discovered recently in patients with essential thrombocythemia (ET) or primary myelofibrosis (PMF)who lacked the JAK2 V617F and MPL W5
Haematopoietic Stem Cell Transplants have been effective in treating numerous disorders of the blood and immune system,including blood cancers like leukemia and bone marrow failure syndromes like myel
LMO2 gene is activated as a result of the chromosomal translocation t(11;14)(p13;q11) o r t(7;11)(q35;p13) and del(11)(p12p13) in T-ALL patients.Here we investigate novel rearr angements involving LMO
Treatment of high-risk acute leukemia by allogeneic hematopoietic stem cell transplantation (HSCT) is an accepted therapeutic strategy.In recent years,cord blood (CB) has emerged as a feasible alterna