【摘 要】
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Ras is a well-known oncogene, which causes cell transformation and tumorigenesis.Plasma membrane translocation of prenylated Ras is a critical step for EGF-stimulated activation of Ras and Ras-regulat
【机 构】
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Children's Research Institute, Medical College of Wisconsin, Milwaukee, WI 53226, USA;Dalian Instit
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Ras is a well-known oncogene, which causes cell transformation and tumorigenesis.Plasma membrane translocation of prenylated Ras is a critical step for EGF-stimulated activation of Ras and Ras-regulated signaling pathway.NgBR was identified as a receptor specific for Nogo-B and contains a conserved hydrophobic pocket that is required for binding prenylated proteins.
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