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To explore angiopoietins (Ang-1, Ang-2), VEGF/VEGF receptor expression and angiogenesis in laryngeal squamous cell carcinoma, paracarcinoma tissues and normal tissurs.Immunohistochemistry were used to detect angiopoietins (Ang-1, Ang-2), VEGF, VEGF receptor protein expression in in laryngeal squamous cell carcinoma, paracarcinoma tissues and their adjacent normal tussues.