Glycogen synthase kinase 3β in the ventral tegmental area mediates diurnal variation of cocaine cond

来源 :第十四届中国神经精神药理学学术会议 | 被引量 : 0次 | 上传用户：qiuyu19900318

【摘要】

：

　　OBJECTIVE To explore role of the brain area as modulator and the underlying mechanism of the diurnal variation of cocaine reward.METHODS We examined the cir

【作者】

：

李素霞;

【出处】

：

第十四届中国神经精神药理学学术会议

【发表日期】

：

2010年期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　OBJECTIVE To explore role of the brain area as modulator and the underlying mechanism of the diurnal variation of cocaine reward.METHODS We examined the circadian rhythm of GSK-3β activity in SCN and reward-related brain areas in naive rats, day and night influence the acquisition of cocaine conditioned place preference (CPP) , cocaine CPP influence the GSK-3β activity in the brain areas described above, and the effect of GSK-3β inhibitor SB216763 microinjected bilateral VTA on cocaine CPP.

其他文献

Receptor binding and function of Y-QA14,a Dopamine D3 receptor ligand

　　OBJECTIVE To investigate the Selectivity and function of Y-QA14, a novel human Dopamine D3 receptor lig and.METHODS Receptor-binding assays was used for the

会议

A resting-state fMRI study on impaired impulsive control in abstinent heroin addicts

　　OBJECTIVE To investigate the neuropsychological underpinnings of this impaired impulsive control network.METHODS Twenty two abstinent heroin dependent (HD)

会议

ATPase6,8在纳米氧化锌诱导HL-7702细胞线粒体能量代谢障碍中作用

目的分析ATPase6,8在纳米氧化锌(ZnO NP)诱导正常人肝细胞(HL-7702)线粒体氧化磷酸化能量代谢障碍中的作用,为ZnO NP疾病防控提供基础数据.方法透射电镜和马尔文粒径分析仪

期刊

纳米氧化锌正常人体肝细胞能量代谢线粒体膜电位线粒体呼吸链复合体VATPase68

淄博市蔬菜重金属污染状况及暴露风险评估

目的评价淄博市蔬菜中砷(As)、镉(Cd)、铅(Pb)和汞(Hg)的污染状况,评估经膳食途径摄入重金属的人体健康风险.方法对2015-2019年采集的612份叶菜类、根菜类、果菜类和茎菜类

期刊

蔬菜重金属污染风险评估

Heroin abuse and dependence using intravenous drug serf-administration in rat

　　OBJECTIVE To investigate the training, extinc tion with cue isolation and reinstatement models of heroin see king.METHODS Training: Male Sprague-Dawley rats

会议

Interactions of μ-opioid receptor and IRAS,a candidate for imidazoline I1 receptor

　　OBJECTIVE To explore whether the interaction occures between MOR and imidazoline receptor antisera-selected (IRAS) and that is responsible for I1 R regulati

会议

Effect of glycine site/NMDA receptor agonist d-CyCloserine on opioid dependence

　　OBJECTIVE To investigate the effect of d-Cycloserine (DCS) on morphine-induced conditioned place preference (CPP) and heroin-induced self-administration (SA

会议

Neural Correlates of Amygdala Functional Connectivity on Abstinent Heroin Addicts

　　OBJECTIVE Utilized resting-state functional con nectivity MRI (fcMRI) to investigate relationship of the altera tion in the amygdala functional connectivity

会议

Independence of Phosphorylation of ERK induced by μ receptor activation on Phosphatidylethanolamine

　　OBJECTIVE To examine whether PEBP partici pates in opioid dependence through modulating activation of MAPK pathway.METHODS AND RESULTS In CHO cell stably ex

会议

5-HT2C受体激动剂Ro60-0175抑制环境和线索诱导的大鼠海洛因复吸行为

　　目的观察5-HT2C受体激动剂Ro60-0175对大鼠环境和线索诱导的海洛因复吸的影响.方法成年雄性SpragueDawley大鼠建立海洛因自身给药模型,固定比率程序FR1,每天4h,持续10

会议

5-HT2C受体激动剂抑制环境线索诱导大鼠海洛因复吸

Glycogen synthase kinase 3β in the ventral tegmental area mediates diurnal variation of cocaine cond

与本文相关的学术论文