INTRODUCTION Genome-wide association studies (GWAS) typically using single nucleotide polymorphism (SNP) as the basic units of analysis is a convenient strategy of genetic studies and has led to the d
背景早在20世纪30-40年代国外的科学家们就发现日照长短能控制水貂、黄鼬等的毛皮生长周期,使毛皮提早成熟。近年来研究表明通过人为控制光照时间长短,能使非长绒期的绒山羊长出一定产量的羊绒,实现增绒的目的,但具体分子机制并不清楚,因此有必要进行系统研究。
引言 随着基因组测序技术的飞速发展,针对畜禽群体的全基因组序列数据进行遗传评估与育种等相关研究将成为动物遗传育种的重要发展方向和研究热点。但是,目前全基因组测序成本还相对较高,对全群进行全基因组测序来实施基因组选择(GS)以及全基因组关联分析(GWAS)还难以现实,因此如何准确有效地利用基因型填充技术(Howie,Donnelly,& Marchini,2009)芯片填充至全基因组序列数据具有重要
[Background]China has a great diversity of ecosystems and an abundance of cattle resources,with nearly 30 million indigenous cattle of 53 indigenous cattle breeds.Traditionally, Chinese indigenous bre
INTRODUCTION Genomic selection has been demonstrated to be a powerful technology that is expected to revolutionize animal breeding through the use of dense markers covering the whole genome.genome. Ho