Coronavirus Papain-Like Proteases Induce Incomplete Autophagy Through Interacting with Beclin 1

来源 :第十届全国病毒学学术研讨会 | 被引量 : 0次 | 上传用户:fircold
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  Autophagy is a cellular catabolic process that sequesters cargo in double-membraned autophagosome and delivers the cargo to lysosomes to be degraded for recycling resource for cells.Autophagy plays important roles in modulating viral replication and antiviral innate and adaptive immune response.Previous studies demonstrated that coronavirus infection is associated with the autophagic process; however, the underlying mechanisms for autophagy induction are largely unknown.
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