Design,Construction,Characterization and Application of Chitosan Derivatives with pH Response and Su

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  How to realize high sensitivity analysis of the thiol-containing peptides from cell using Mass spectrometry is still a challenge,as thiol-free peptides is too high compared with thiol-containing peptides,causing the thiol-peptide-mass spectrometry signals was masked by thiol-free peptides.
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In biological systems,polarity is one of the microenvironment parameters associated with cellular status.Disorders in microenvironmental polarity were frequently observed in specific diseases such as
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Monitoring the activity of ALP in serum can help diagnose a variety of diseases including bone and liver diseases.[1] There has been growing interest in developing new chemical tools for monitoring AL