【摘 要】
:
Metastatic cancer stem cells (mCSCs) have been shown to be essential seeds initiating a cancer metastasis.However, the biology of mCSCs is still poorly understood.We herein used a lymph node metastati
【机 构】
:
Vectorite Biomedica Inc.Taiwan
论文部分内容阅读
Metastatic cancer stem cells (mCSCs) have been shown to be essential seeds initiating a cancer metastasis.However, the biology of mCSCs is still poorly understood.We herein used a lymph node metastatic CEA-producing GI-carcinoma cell line, UP-LN1, characterized by its persistent appearance of adherent (A) and floating (F) cells in culture passages, to determine which cell subset would be the major niche for CSCs and the induction mechanisms of mCSCs from CSCs.
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