A Straightforward Entry to Chiral Cyclopropyl Carbocyclic Purine Nucleosides via Asymmetric Intramol

来源 :河南省化学会2016年学术年会 | 被引量 : 0次 | 上传用户:wilsonpfan
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  Chiral carbocyclic purine nucleosides have been the focus of much attention in the search for new antiviral and antitumor therapeutic agents.Cyclopentyl carbocyclic guanosine nucleoside Carbovir has been approved by the FDA for the treatment of HIV infection,and the cyclobutyl carbocyclic guanosine nucleoside Lobucavir has been applied in the anti-HBV infection.
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