TCAB1(Telomere Cajal Body protein 1)is an important component of Cajal body.It participates in telomere elongation,repairs DNA double strands break and promotes tumor development.
Anaplastic thyroid cancer(ATC)is the most aggressive human thyroid malignancy,characterized by dedifferentiation and resistance to radioiodine therapy.
Malignant tumors are serious diseases that seriously threaten human health.The treatment is mainly based on surgical treatment,radiation therapy,chemotherapy and immunotherapy in recent years.
Maintenance of genomic stability is critical for the proper function of organisms.When DNA damage occurs and is detected,a series of repair proteins sequentially accumulate at the damaged site and ind
The HECT type E3 ligases are key regulators of cell growth and proliferation,and malfunctions of these enzymes are associated with a broad range of human tumors and other diseases.
L-periaxin is an important scaffold protein in nerve cells of mammals.During the development and maturation of Schwann cells,L-periaxin redistributes its subcellular localization from the nucleus to t
In the peripheral nervous system(PNS),Schwann cells(SCs)are required for the myelination of axons.Periaxin(PRX),one of the myelination proteins expressed in SCs,is critical for the normal development