顽固性腹胀是慢性重型肝炎(简称慢重肝)终末期临床表现之一。了解其病理生理有利于临床制定合理的治疗方案,降低病死率及估计预后。正常人体肠道内24h气体大约25 000ml,其生成和排泄保持动态平衡。气体的来源有3条途径:①正常人体进食后食物在消化道停留的时间大致为:胃内3～4h,小肠内6～8h,大肠内8～12h。饮食时有少量空气温和在食物中,随着吞咽动作进入胃肠;②吸气时由于胸腔负压,食道口轻微开 Intractable bloating is one of the end-stage clinical manifestations of chronic severe hepatitis (referred to as slow liver). To understand its pathophysiology is conducive to the development of a reasonable clinical treatment plan, reduce mortality and prognosis. Normal human intestinal gas 24h about 25 000ml, its production and excretion to maintain homeostasis. There are three sources of gas sources: ① normal human food intake of food in the digestive tract time is roughly: 3 ~ 4h in the stomach, 6 ~ 8h in the small intestine, 8 ~ 12h in the large intestine. A small amount of air when eating mild food, with swallowing into the gastrointestinal tract; ② suction due to chest pressure, slightly open the mouth of the esophagus