Liver targeting of polysaccharide from the root of Angelica sinensis (Oliv.) Diels

来源 :2015年中国药物制剂大会、中国药学会药剂专业委员会2015年学术年会暨国际控释协会中国分会2015年学术年会 | 被引量 : 0次 | 上传用户:seanchn
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  A novel homogeneous polysaccharide named ASP was extracted from the roots of Angelica sinensis (Oliv.) Diels and labeled with FITC according to the method of Belder and Granath.In the present study, we investigated the uptake of ASP between hepatoma cells such as HepG2 cell and Bel-7402 cell,and non-hepatoma cells like Hela cell, and the in vivo distribution of ASP in healthy Babl/c mice.The mice was intravenously injected with ASP labeled with FITC and the concentrations of ASP in different tissues were detected by high performance liquid chromatography.
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