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5. Reversal of multidrug resistance by sequential treatment with redox-responsive glucolipid conjugate

Reversal of multidrug resistance by sequential treatment with redox-responsive glucolipid conjugate

来源 :2016年中国药物制剂大会、中国药学会药剂专业委员会2016年学术年会、中国化学制药工业协会固体制剂专业委员会2016年 | 被引量 : 0次 | 上传用户：fkswind

【摘 要】

：

Multi-drug resistance(MDR)is one of the major obstacles in cancer chemotherapy.Small interference RNA(siRNA)plays an important role on down-regulation of P-glycoprotein(P-gp),which is a major drug eff

【作 者】

：

Binbin Lu Hong Yuan Fuqiang Hu 

【机 构】

：

College of Pharmaceutocal Science,Zhejiang University,866 Yuhangtang Road,Hangzhou 310058,P.R.China

【出 处】

：

2016年中国药物制剂大会、中国药学会药剂专业委员会2016年学术年会、中国化学制药工业协会固体制剂专业委员会2016年

【发表日期】

：

2016年4期

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　　Multi-drug resistance(MDR)is one of the major obstacles in cancer chemotherapy.Small interference RNA(siRNA)plays an important role on down-regulation of P-glycoprotein(P-gp),which is a major drug efflux transporter overexpressed on multi-drug-resistant(MDR)tumor cells.

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