AIM: Investigate the effect of PHF1027 (a formula consists of gypenosides and other two components, data not published) on blood lipid and glucose regulation in mice.METHODS: Fourty four mice were ran
目的:研究三公膏对小鼠的补益作用.方法:对照组小鼠灌胃生理盐水,实验组以样品浸膏1.508g/ (kg.d)剂量灌胃"三公膏",每日给药1次,连续给药5d.观察雄性小鼠与发情期雌鼠交配过程中的捕捉次数及捕捉潜伏期;测定小鼠常压耐缺氧存活时间.结果:观察小鼠交配实验可得,与空白对照组比较,"三公膏"实验组小鼠捕捉潜伏期(P＜0.05)明显缩短,捕捉次数(P＜0.01)显著提高,小鼠性欲增强,三公膏对
Aim of the study: This paper was to establish a more specific, efficient, and conveniently mathematical kinetic model of the components extracted from one of Chinese herbal formula named BYHWD (Buyang
目的:金钗石斛总生物碱(Dendrobium nobile Lindl.Alkaloids,DNLA)已被证实对糖尿病大鼠、高脂饮食饲养大鼠及肾上腺素性高血糖小鼠有降血糖和降血脂作用.本实验旨在进一步研究DNLA对小鼠肝脏糖脂代谢基因的关键调控因子Sirt1及其调控的相关基因表达的影响.方法:采用雄性KM小鼠,连续8天灌胃DNLA(120 mg/kg、240 mg/kg),分离肝脏,提取总RNA,
Objective: To investigate the effect of SBF on cortical cytoplasm apoptotic factors disturbances induced by complex Aβ25-35 in rats.Methods: The cerebral injuries model was established by rats receive
Objective: This work aims to investigate the protective effect of icaritin (ICT) on amyloid-β peptide (Aβ)-induced neurotoxicity, and then to explore that if this effect of ICT is through increasing A
Objective: To investigate the effects of icariin (ICA) on the proliferation of pulmonary artery smooth muscle cell (PASMC) induced by endothelin-1 (ET-1), and explore its mechanisms.Methods: PASMC fro
Objective: To investigate the protective effects of icariin (ICA), one of active components of epimedium, on Lipopolysaccharide (LPS)-induced dopaminergic (DA) neuronal damage in rats.Methods: Male ra
抑郁症是由多种因素引起的情感障碍性疾病，其特点是发病率高、致死率高和复发率高，给社会带来了严重的经济负担。抑郁症的发病机制复杂，现有研究表明其发病机制主要涉及单胺递质、下丘脑-垂体肾上腺轴功能失调、神经再生障碍和表观遗传学等，但是针对这些机制的治疗药物缺乏治疗效果并伴有副反应。因此，进一步研究抑郁症的发病机制至关重要。
Icariside Ⅱ (ICS Ⅱ) is a natural product extracted from Herba Epimedii Maxim and possesses diverse biological activities including antineoplastic effects.Recently, the role of ICS Ⅱ has been extensive