It has taken us millions of years to discover that the genome can be artificially challenged but only a few dozen of years to develop and refine the necessary m
Generation of genetically manipulated animal models is costly, time consuming and requires multiple resources.A centralized core facility consolidates the expen
It is increasingly recognized that the genetic background (i.e.all genomic sequences other than the gene(s) of interest) can have profound influences on the phe
Like any organization working with large amounts of data, research laboratories can benefit greatly from using computer software to help automate otherwise manu
I was introduced to embryonic stem cells in 1980 as an undergraduate.Martin Evans my undergraduate project advisor asked me to isolate embryonic stem [ES] cells
The challenges for modern genetic research facilities are numerous.These include the need for ever improving levels of animal health status, regulatory change a
With the advent of transgenic technologies, the number of mice shipped around the world has increased exponentially.Whereas once standard inbred lines were obta
Assisted reproductive technologies (ARTs), such as cryopreservation, are commonly used to manage mouse colonies.More recently these technologies are being used