IMMEDIATE EARLY GENE X1 (IEX-1) AMELIORATES VASCULAR CALCIFICATION THROUGH INHIBITING MITOCHONDRIAL

来源 :19th Annual Scientific Meeting of the Institute of Cardiovas | 被引量 : 0次 | 上传用户：suease

【摘要】

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【作者】

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Y Zhao MM Zhao MJ Xu X Wang

【机构】

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Department of Physiology and Pathophysiology,Basic Medical College,Peking University,China

【出处】

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19th Annual Scientific Meeting of the Institute of Cardiovas

【发表日期】

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2015年9期

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Introduction: Vascular calcification (VC) is the major risk factor for cardiovascular mortality in chronic renal failure (CRF) patients, but the pathogenesis remains largely unknown and effective therapeutic targets are urgent to be explored.The Immediate Early Gene X-1 (IEX-1) plays a role in controlling cellular growth and differentiation.As IEX-1 expressed in the cartilage tissue and it can modulate protein phosphatase, we aimed to study whether IEX-1 affects VC.

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IMMEDIATE EARLY GENE X1 (IEX-1) AMELIORATES VASCULAR CALCIFICATION THROUGH INHIBITING MITOCHONDRIAL

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