富马酸喹硫平对精神分裂症急性期阴性症状和抑郁症状的疗效研究

来源 :2014中华医学会第十二次全国精神医学学术会议 | 被引量 : 0次 | 上传用户:BeginJava123
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目的 评价富马酸喹硫平单药治疗精神分裂症急性期阴性症状和抑郁症状的疗效.方法 采用前瞻性、单组、开放性的研究设计.纳入符合ICD-10精神分裂症诊断标准的124例精神分裂症急性期住院患者,予富马酸喹硫平600~750mg/d单药治疗,观察时间为24周,在基线、治疗第1周末、第8周末及第24周末评估患者的治疗效果及安全性.疗效指标为阳性与阴性症状综合征量表(PANSS)评分变化、蒙哥马利抑郁量表(MADRS).安全性指标包括不良事件的评估、实验室检查和生命体征等.
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目的 评价富马酸喹硫平600 ~ 750mg/d单药治疗精神分裂症急性期兴奋症状的疗效和安全性.方法 采用前瞻性、单组、开放性的设计,纳入符合ICD-10诊断标准的精神分裂症急性期患者124例,予喹硫平600~750mg/d单药治疗.观察时间为24周,在基线、治疗第1周末、第8周末及第24周末评估患者的治疗效果及安全性.疗效指标为阳性与阴性症状综合症量表(positive and negative
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