【摘 要】
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Objective Objective: While anti-HER2 tyrosine kinase inhibitors(TKIs)have radically prolonged survival and improved the prognosis in HER2-positive breast cancer patients,resistance to these therapies
【机 构】
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National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy
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Objective Objective: While anti-HER2 tyrosine kinase inhibitors(TKIs)have radically prolonged survival and improved the prognosis in HER2-positive breast cancer patients,resistance to these therapies is a constant obstacle leading to treatment failure and tumor recurrence.We hope to find a candidate gene related to sensitivity of anti-HER2 targeted therapy,providing a promising therapeutic target for HER2-positive breast cancer patients with resistance to anti-HER2 targeted oncotherapy.
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