【摘 要】
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Catalytic asymmetric 1,3-dipolar cycloaddition of azomethine ylides with 2-π dipolarophiles was widely utilized for the construction of five-membered pyrrolidine heterocycles.[1] However, this methodo
【机 构】
：
College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, 430072, China
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Catalytic asymmetric 1,3-dipolar cycloaddition of azomethine ylides with 2-π dipolarophiles was widely utilized for the construction of five-membered pyrrolidine heterocycles.[1] However, this methodology has rarely been employed to construct six-membered heterocycles.Recently, fulvenes[2] and tropone[3] were employed as 6-π dipolarophiles in 1,3-dipolar [3+6]-cycloaddition delivering six-membered heterocycles.The intrinsic nonbenzenoid aromatic characteristic exhibited by the resonance forms of fulvenes and tropone provides the driving force for those transformations.
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