CT引导放射性I-125粒子植入治疗头颈部复发或转移癌剂量学分析

来源 :2015年北京放射肿瘤年会 | 被引量 : 0次 | 上传用户:q3177848
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目的:探讨头颈部复发或转移癌在CT引导下使用放射性I-125粒子植入治疗的剂量分布. 方法:选择10例2015年1月至6月在北京大学第三医院接受了CT引导下放射性I-125粒子植入的头颈部复发或转移癌的患者,计划处方剂量D90(90%靶区体积接受的剂量)为100-120 Gy.在CT实时图像引导下进针,利用M ick枪后退式植入粒子,粒子针间距1cm,平行排列,术后即刻行CT扫描,应用北航科霖三维治疗计划系统进行剂量学验证. 结果:靶区平均体积为27.69ml,平均植入粒子39.1颗,单颗粒子活度为0.5-0.7mCi平均植入粒子活度1.03mCi/ml,平均D90为113.08Gy,平均V100(靶区接受100%处方剂量的体积百分比)为88.39%,平均V150是64.95%. 结论:CT引导放射性I-125粒子植入治疗头颈部复发或转移癌可以实现预期的剂量分布.
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