Background Accumulating evidence suggests the butyrate-producing bacteria,such as Roseburia/Eubacterium group,may play an important role in maintaining the human gut health.In this work we aim to inve
Objective Pulmonary tuberculosis (TB) has gained attention in recent decades because of its rising incidence trend; simultaneously,increasing numbers of studies have identified the relationship betwee
Objective Community-acquired pneumonia (CAP) is a major concern in hospitals and the bacterial community of which has not been systemically discussed yet.Sputum from patients in the acute stages is a
抗菌药物治疗不仅会影响致病菌，而且影响肠内正常菌群。此外，对抗菌药物耐药的菌株可以持续的在人类宿主环境中有选择性地生存。一些实验方法已经揭示了使用抗菌药物后肠道菌群的紊乱，特别是一些菌群对抗菌药物敏感或者选择性耐药的问题。在人类肠道中，抗菌药物的使用可能导致耐药基因的长期存在。因此需要加强抗菌药物的管理，否则可能加剧新兴耐药菌株的形成。
本实验通过微量液体稀释法测定抗菌多肽RISE-AP12TM对浮游状态下牙龈卟啉单胞菌(Porphyromonas gingivalisW83,P.gingivalis W83)的最小抑菌浓度和最小杀菌浓度,了解抗菌多肽RISE-AP12TM对P.gingivalis W83的生长抑制作用;应用real-time PCR技术检测抗菌多肽RISE-AP12TM对P.gingivalis W83脂蛋白基
急性淋巴细胞白血病(ALL)是我国儿童期发病率最高的恶性肿瘤,大剂量甲氨喋呤(HDMTX)化疗是治疗儿童ALL和提高其生存率的有效方法.对HDMTX化疗ALL患儿检测肠道菌群可明确其变化;测定血内毒素和血二胺氧化酶(DAO)水平,可评估肠粘膜的损伤情况;测定血胃泌素(GAS)、血管活性肠肽(VIP)和P物质(SP)水平,可了解胃肠激素的变化.本文通过病例对照试验发现，ALL患儿和在HDMTX化疗过
本文以2012年5月至2013年6月在重庆医科大学附属儿童医院内外科住院患儿为研究对象,取新鲜大便约5g,装入无菌容器内,立即送检.通过肠道菌群粪便涂片检查方法,参照张秀荣《肠道菌群粪便涂片检查图谱》,由专人直接涂片革兰染色查菌,观察其细菌成分的百分比(真菌及菌丝、阴性杆菌、阳性杆菌、阴性球菌、阳性球菌、球杆比及球杆比变化),从微生态学的角度研究使用抗生素后,患儿肠道菌群的变化,并分析其临床特征.
Objective To study the molecular epidemiology of GII.4 Sydney-associated diarrhea in Beijing,China in the winter of 2012-13 during the global epidemic associated with the emergence of GII.4 Sydney.Met
Objective To analyze the tendency and antimicrobial resistance of clinical isolates in our hospital from 2008 to 2010.Methods Disk diffusion method was used to determine the antimicrobial susceptibili