【摘 要】
:
丙型肝炎病毒(Hepatitis C virus,HCV)是造成慢性肝炎、肝硬化及肝癌的重要原因之一.目前全球约有一亿八千万人口感染HCV(感染率:3%).在我国,HCV是仅次于乙型肝炎病毒(Hepatitis B virus,HBV)引起慢性肝炎的因素.近期研究发现,IL-28B的基因多态性不仅是目前发现的丙型肝炎疗效的重要预测因子,还与急性丙肝病毒感染的自发性清除有很大的关系.本文就目前的研究
【机 构】
:
河南省人民医院感染科 450003
【出 处】
:
中华医学会第四次全国肝纤维化、肝硬化学术会议
论文部分内容阅读
丙型肝炎病毒(Hepatitis C virus,HCV)是造成慢性肝炎、肝硬化及肝癌的重要原因之一.目前全球约有一亿八千万人口感染HCV(感染率:3%).在我国,HCV是仅次于乙型肝炎病毒(Hepatitis B virus,HBV)引起慢性肝炎的因素.近期研究发现,IL-28B的基因多态性不仅是目前发现的丙型肝炎疗效的重要预测因子,还与急性丙肝病毒感染的自发性清除有很大的关系.本文就目前的研究现状对IL-28B的基因多态性与慢性丙型肝炎病毒感染的关系做以下综述,并讨论相关研究如何预测慢性丙肝的临床疗效和制定个体化治疗方案提供参考.
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