【摘 要】
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In most mammals, mature oocytes after ovulation undergo a process of deterioration in quality,which is called oocyte aging.Oocyte aging after ovulation significantly affects embryo development.Inhibit
【出 处】
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中华医学会第九次全国生殖医学学术会议
论文部分内容阅读
In most mammals, mature oocytes after ovulation undergo a process of deterioration in quality,which is called oocyte aging.Oocyte aging after ovulation significantly affects embryo development.Inhibiting oocyte postovulatory aging is important both for healthy reproduction and for assisted reproduction techniques.GRIM-19 is belongs to IFN/RA induced cell death regulators,which is involved in the process of regulation in proliferation, apoptosis of cells and its expression decreased or mutation can lead to abnormal proliferation and malignant transformation of cells.There is no research which reported the expression and location of GRIM-19 in the mouse oocyte so far.
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