【摘 要】
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From 1964 on, the EORTC Lymphoma Group has conducted 9 consecutive randomised phase Ⅲ trials on early stages Hodgkin lymphoma (HL) aiming at increasing efficacy while decreasing shortand long-term tox
【机 构】
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University of Antwerp, ZNAMiddelheim/UZAntwerpen Belgium
论文部分内容阅读
From 1964 on, the EORTC Lymphoma Group has conducted 9 consecutive randomised phase Ⅲ trials on early stages Hodgkin lymphoma (HL) aiming at increasing efficacy while decreasing shortand long-term toxicity.Event-free and overall survival significantly improved from about 50%and 70% to over 80% and 90% more recently.Identification of prognostic subgroups appeared a successful method to tailor treatment strategies.Radiotherapy fields have become more restricted whereas chemotherapy has become standard.The subtotal nodal fields were reduced to involved fields, and recently in the H10 (limited stage HL) to involved nodes.
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