【摘 要】
：
AIM To prepare and research the characteristics of puerarin as a certified reference materials(CRMs) for the crucial quality assurance to validate measurementmethods which deliver reliable and accurat
【机 构】
：
Center of Pharmaceutical Polymorph,Institute of Materia Medica,Chinese Academy of Medical Sciences a
【出 处】
：
第二届世界天然药物和传统药物药理学学术会议
论文部分内容阅读
AIM To prepare and research the characteristics of puerarin as a certified reference materials(CRMs) for the crucial quality assurance to validate measurementmethods which deliver reliable and accurate results.METHODS Sample preparation,homogeneity study, stability study, value characterization, and evaluation of uncertainty of a new CRM of puerarin are researched.The homogeneity was checked by differential scanning calorimetry method.Thestabilitywastested under differentstorageconditinns.RESULTS The CRM described above was homogeneousandstable at 25℃ for at least one year.The certified value of puerarin CRM is 99.66% with an extended uncertainty of 0.48% (k =2).CONCLUSION The new CRM of pucrarin can be used to validate analytical methods, improve the accuracy and comparability of measurement data, establish meteorological traceability of analytical resuhsas well as control the quality of puerarin in relevant food and pharmaceutical formulations.
其他文献
AIM Human dermal fibroblasts in a dermal tissue model show reduced proliferation or cell-matrix contact inhibition (CMI), distinct from cell-cell contact inhibition (CCI) at confluent.Epidermal growth
AIM To investigate the effects of different concentrations of calycosin on estrogen receptor-positive human breast cancer cells in vitro and in vivo.METHODS In the present study, ER-positive MCF-7, T4
AIM To observe the antihypertensive effect of linarin combined with luteolin on SHR.METHODS ① The singledose test: The spontaneously hypertensive rats (SHRs) were given linarin combined with luteolin
AIM Compound Danshen tablet (CDT), a Traditional Chinese Medicine, has recently been reported to improve spatial cognition in a rat model of Alzheimers disease.However, in vivo neuroprotective mechani
AIM Methyl salicylate 2-0-β-D-lactoside (MSL) is a novel NSAIDs of molecule chemically related to salicylic acid.It is isolated from a kind of traditional Chinese medicine, Gaultheria yunnanensis (FRA
AIM Referring to the relation between hypertension and excessive drinking and high fat diet, we established the hypertension model rats by feeding with alcohol and high glucose and fat diet, which is
AIM To study the high homocysteine rats, to explore the sponge body homocysteine hemoglobin content of carbon monoxide/add oxygen enzyme 2 (CO/HO-2) the influence of the system.METHODS The forty male
AIM The aim of the present study was to evaluate the effect of salvianolie acid A (SalA) on the pathological progression of hepatic fibrosis in rats with type 2 diabetes and investigate its liver-prot
AIM To investigate whether Salvianolic acid A (SAA) exhibits its protective effects in rots through epoxide hydrolase (sEH) and Epexyeicosatrienoic acids (EETs).METHODS Heart and cerebral ischemia in
AIM To investigate the effects and the underlying mechanism of Echinacoside (ECH) against 6-OHDA-induced injury in vitro.METHODS 6-OHDA was added to cultured PC12 cells after pretreatment for 1 h with