Noncoding RNA Identification based on Topology Secondary Structure and Reading Frame in Organelle Ge

来源 :第七届全国生物信息学与系统生物学学术大会 | 被引量 : 0次 | 上传用户:john0620
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Non-coding RNA (ncRNA) genes make transcripts as same as the encoding genes,and ncRNAs directly function as RNAs rather than serve as blueprints for proteins.As the function of ncRNA is closely related to organllie genomes,it is desirable to explore ncRNA function by confirming its provenance.Based on the experimental data,a ncRNAs dataset with less than 80% sequence identity (ncRNA_361)[1]for different organelle genomes is built from NONCODE v3.0[2].The ncRNA sequences from the four kinds of organllie genomes are recognized by using the improved K-minimum increment of diversity classifier (iK-MID) algorithm based on the features from the topology secondary structure and reading frames.
其他文献
Mycoplasma play important roles in the emerging field synthetic biology due to their small genomes and simple metabolic pathways.The distribution of homologous essential genes among different Mycoplas
The accumulation of genome-wide gene expression data provide the opportunity to classify cancer into different subgroups based on gene expression signatures.However,due to the heterogeneity of biologi
While the number of sequenced prokaryotic genomes is growing rapidly,experimentally verified annotation of prokaryotic genome remains patchy and challenging.To facilitate genome annotation efforts for
Protein-RNA complexes formed by specific recognition between RNA and RNA-binding proteins play an important role in biological processes.More than a thousand of such proteins in human are curated and
Backgrounds: In current molecular biology,it becomes more and more important to identify characteristic genes closely correlated with a key biological process from gene expression data.Methods: In thi
MicroRNAs (miRNAs) are endogenously expressed small noncoding RNAs.The genomic locations of animal miRNAs are significantly clustered in discrete loci.We found duplication and de novo formation were i
sRNAs and their targets were usually discovered by bioinformatics prediction combined with experimental verification,which was hampered by the low prediction accuracy and low-throughput.Among the 2792
Horizontal transfer (HT) is the passage of genetic material between non-mating species.Transposable elements (TEs) have inherent ability to mobilize and proliferate within genomes,and over 200 cases o
Pseudogenes,which have long been described as "fossils",play a very important role in eukaryotic genomes.Recently,studies on the so called "junk gene" have attracted more attention.Far from being sile
Long non-coding RNAs (LncRNAs) are typically defined as transcripts longer than 200 nucleotides,participate in transcriptional,epigenetic,or post-transcriptional regulation of gene expression[1].Latel