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  5. Clinical Implication of Microarray-based Immune Response Score in Different Molecular Subtypes of Br

Clinical Implication of Microarray-based Immune Response Score in Different Molecular Subtypes of Br

来源 :2011第四届世界癌症大会暨乳腺癌峰会 | 被引量 : 0次 | 上传用户：lxget
【摘 要】
：
Recently, we developed a molecular subtyping method for breast cancer based on gene expression profiling (BMC Cancer 11;143, 2011).Six molecular subtypes with distinctive biological and clinical chara
【作 者】
：
K.J.Kao Kai-Ming Chang Andrew T.Huang 
【机 构】
：
Koo Foundation SYS Cancer Center Taiwan
【出 处】
：
2011第四届世界癌症大会暨乳腺癌峰会
【发表日期】
：
2011年3期
【关键词】
：
Breast cancer molecular subtypes immune response score prognosis personalized me 
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　　Recently, we developed a molecular subtyping method for breast cancer based on gene expression profiling (BMC Cancer 11;143, 2011).Six molecular subtypes with distinctive biological and clinical characteristics were identified.During the study, differential expression of immune response-related genes within certain molecular subtypes of breast cancer was noted and appeared to associate with risk of distant recurrence.This finding prompted us to further investigate how differential expression of immune response genes might affects risk of distant metastasis in different molecular subtypes of breast cancer.
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