白介素10对哮喘小鼠子宫珠蛋白相关蛋白1和白介素5的影响

来源 :2014中华医学会呼吸病学年会暨第十五次全国呼吸病学学术会议 | 被引量 : 0次 | 上传用户:ccsrg
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目的 通过腹腔注射白介素10,观察哮喘小鼠肺组织中子宫珠蛋白相关蛋白1 (UGRP1)和肺泡灌洗液中白介素5表达.方法 将40只Balb/c雌性小鼠,随机分为哮喘模型组(X)(8只)、IL-10干预组(B1,B2,B3)(24只)、空白对照组(K)(8只).用免疫组化和RT-PCR法检测小鼠肺组织中UGRP1的表达,ELISA检测肺泡灌洗液中UGRP1和IL-5的含量.
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