Raltitrexed induces mitochondrial-mediated apoptosis and upregulates the expression of thymidylate s

来源 :第十七届全国临床肿瘤学大会暨2014年CSCO学术年会 | 被引量 : 0次 | 上传用户:dswwldsw
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Objective: As a specific inhibitor of thymidylate synthase (TS), raltitrexed has been shown to prolong survival for patients with advanced gastric cancer in our clinical practice.However, the possible mechanisms of raltitrexed-induced apoptosis is still unknown in gastric cancer.The present study aimed to investigate the apoptosis mechanisms of raltitrexed in human gastric cancer SGC7901 cells.
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