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Introduction: Nicotinamide phosphoribosyltransferase(Nampt)is a crucial coenzyme in cellular redox reactions.Inside the cell,Nampt(iNampt)acts as a rate-limiting enzyme in the production of nicotimamide adrenine dinucleotide(NAD),and outside the cell(eNampt),it serves as a proinflammatory adipocytokine.