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一氧化氮(NO)作为信使物质或效应分子在心血管、免疫等系统发挥重要的生理作用[1]。由于NO 的多种生物活性以及"双刃剑"的作用，利用高浓度的NO来实现抗肿瘤则需要选择性和靶向性地将NO定点输送到肿瘤细胞中，尽可能的减少NO 在非靶部位的释放而带来的副作用。
纳米一氧化氮传递系统的设计、合成与初步生物学评价
【摘 要】
：
一氧化氮(NO)作为信使物质或效应分子在心血管、免疫等系统发挥重要的生理作用[1]。由于NO 的多种生物活性以及"双刃剑"的作用，利用高浓度的NO来实现抗肿瘤则需要选择性和靶向性地将NO定点输送到肿瘤细胞中，尽可能的减少NO 在非靶部位的释放而带来的副作用。
【机 构】
：
中国药科大学新药研究中心,南京210009
【出 处】
：
2015年全国药物化学学术会议暨第五届中英药物化学学术会议
【发表日期】
：
2015年3期
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