SHBG基因多态性与河南汉族人群男性不育的相关性研究

来源 :第十二次全国医学遗传学学术会议 | 被引量 : 0次 | 上传用户：dulcimerqin

【摘要】

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目的探讨SHBG基因多态性与男性不育的关系。方法采用病例-对照研究方法，利用PCR-RFLP技术对正常男性与原发性男性不育患者SHBG基因的rs6259位点和rs727428位点多态性进行分析，并分别计算两组人群SHBG基因型和等位基因的分布频率。结果 SHBG基因rs6259 A等位基因在男性不育患者组明显高于对照组，而rs727428位点CC基因型的比例则显著低于对照组。结论 SHBG基因

【作者】

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崔元戎马宇飞郭艺红李晓文陈辉

【机构】

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郑州大学第三附属医院生殖中心,郑州大学基础医学院细胞生物学与医学遗传学教研室郑州大学基础医学院细

【出处】

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第十二次全国医学遗传学学术会议

【发表日期】

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2013年4期

【关键词】

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SHBG 基因多态性男性不育

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SHBG基因多态性与河南汉族人群男性不育的相关性研究

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